This partnership as part of the iTech Awards Program is a tremendous opportunity to accelerate our mission of improving treatment outcomes for intravenously-administered therapeutics. We are proud that Sanofi has recognized the strategic opportunity to evaluate pairing our Nanoprimer technology with their gene therapy pipeline, potentially expanding the ability to offer the benefits of these product candidates to more patients. We look forward to pairing our scientific expertise with Sanofi’s considerable resources so that we can begin generating data in gene therapy and continue to evolve the therapeutic paradigm.
Matthieu Germain, CEO of Curadigm
Paris, France, Cambridge, Massachusetts (USA), 25 January 2021 – Curadigm (the “Company”), an early-stage nanotechnology company dedicated to improving treatment outcomes by shifting the therapeutic delivery paradigm, today announced the selection of its project involving proprietary Nanoprimer technology for the Sanofi iTech Awards program. The Sanofi iTech Awards program aims to identify external innovations with the potential to significantly improve drug discovery and design, drug delivery and drug development within Sanofi. Curadigm’s project selection for this program underscores the potential of Curadigm’s Nanoprimer to address barriers to the development of promising therapeutics, including nucleic acid-based product candidates.
Nanoprimer technology is designed to precisely and temporarily occupy the therapeutic clearance pathways in the liver. It is administered intravenously, immediately before administration of the therapy, and acts to prevent rapid clearance—thereby increasing bioavailability and subsequent accumulation of therapeutics in the targeted tissues. (Watch the video)
The selection to the Sanofi iTech Awards Program involves 100 k€ in funding for one year and scientific exchanges with Sanofi to establish proof of concept. The goal of the project will be to prove that Curadigm’s Nanoprimer can improve biodistribution and enhance the efficiency of gene therapy product candidates, potentially expanding and accelerating the ability of these product candidates to provide significant benefits to patients.